yes you can..basic principles as same as petrol however you must use NG fuel injection system and those cost a lot!!!
Using a carburetor could be dangerous because it requires mounting at the intake of super/turbo charger. A mixture of fuel and air under pressure is a bomb!!
On the advantage side, it would be useless as the amount of CNG on board in average car is useless to deliver any serious power. Your mileage may be 20Km/per fillup!!