The 1UZ is a very versatile engine, Hasan. If you read up on it, it has successfully been used to power not just cars, but boats, and aeroplanes as well! Tuners have supercharged earlier generation 1UZs to the order of 550+ bhp, on stock internals. It's been used with automatic gearboxes, manual gearboxes, 4wd gearboxes, and pretty much everything under the sun. So...modifying a 1UZ to be adapted to a 4WD gear isn't really impossible.
Our very own Suhaib Kiani is somewhat of an expert on these radical, ground-breaking mods.
When it comes to a mechanical simpleton like me, though, I'm more inclined to sticking to easily-available, ready-bolted things. And since I have a very good experience of the 1UZ VVTi with its automatic gearbox in a couple of cars I own. In fact, not JUST my 65 and 67 Impalas have 1UZs. I have a '73 Mustang which came fitted with a 3rd Generation 1UZ with a 4 speed auto, and a '74 Camaro which had a 2nd Generation 1UZ with a 4 speed auto.