Sir this is why a definite budget bracket should always be given before hand so that we could help you accordingly.
Now that you've told its 80k, i'd be glad to come up with a most cost effective solution.
The above mentioned items are high end items.
In 80k
Pioneer 4250,4350:35k
Component Speakers:Fusion NV Components: 15k or Pioneer D1720: 9K or JBL P608c:8-9k
Amplification: Soundstream XTA or TRA series amplifier:15-18k, or Any good 4 channel amplifier, Pioneer, Kenwood, But i'd like to mention one thing here that if you want extreme bass reproduction, you would need a dedicated amplifier, Mono Amplifier, for the sub, although Soundstreams would play the sub really well, but the Kenwood or Pioneer 4 channels are not meant for SPL.
Another solution to this could be that you buy a Kenwood M-845 4 channel amplifier and power your components and coaxial speakers through that, and also buy a kenwood mono amplifier, M845 would cost around 10k and Kenwood mono would cost around 12k.
Wiring:Fusion Wiring Kit:3.5k
Sub Woofer: Pioneer W306c:3.5k ( second hand, new one costs 8k, and isnt usually available in the market ), JBL GT-5, JL Audio 12w3v2
Sub Enclosure the same as above.
Rear Coaxials: Sony 6.5inch speakers for the rears ( play these directly from the HU ) 4.5k
This adds up to 80k, give or take a few.
The prices ive mentioned might vary from shop to shop, but they would be along these lines.
If you do not wish to use an Audio Video DVD Headunit, you may look into other single din players offered by pioneer or kenwood, but make sure they have atleast 2-3 RCA out.
In Islamabad you could visit madhouse12 ( PM him ) and he would gladly help you source all these items.