Depends on the target market.
As with the previous gen, they'll only offer the 3.5L V6 in FWD; if it were AWD I would get it over any other version. Power matters to me, over fuel and reg. I'm sure there are similar people around.
But I'll go for the Hybrid AWD because that's the one they'll pitch as the flagship with the full bells and whistles. Not as much oomph as the V6, but plenty nonetheless, as I observed in the Santa Fe Hybrid and Sportage L test drives (same engine).