Best cure option for thalassemia currently in pakistan or anywhere in the world is BMT. But that can only be told after looking at the patient's condition that can he handle a BMT.
In simplified terms, first pt is cross matched with the donors a pt and his family can nominate donors so you can be on the list the best possible match gets the call, then pt blood producing cells are annihilated using chemotherapy, this is the difficult part for the pt to withstand as high chances of infection are there, now new healthy donor cells are transplanted.
For best diagnosis or BMT, our country pakistan has nearly the same facilities like any other country if you have money, best is shaukat khanum, aga khan, shifa international, all of them have american certified and trained physicians who perform BMT as it is specialized job only a certified BMT specialist can perform not all hematologist or oncologist are qualified in this procedure.
Gene therapy is taking place I saw on net in memorial sloan kettering but will be too expensive and is in phase 1 trial at the moment that means it is under research and will take about 5-10 years to be available in the market. If BMT is available in pakistan and it can cure the disease depending case to case specially in your city why go for a more expensive option which might be 5-10 times more expensive.