Well in terms of driving pleasure: Civic is better, it has a certain punch to it. Comfort wise Prius is better in terms of seats but the shaking on cateyes, bumps and potholes feel more. Like the vibration feels more in the suspension, probably the extra low clearance amd suspension are culprit for this. With 4 onboard Prius touches breakers. Safety wise Prius has more airbags: 8 in case of my car. The only missing features I can immediately think of are automatic vipers and light. But on the other hand Civic has additional Brake hold, Sunroof, Rear AC vents and E-brake.
Braking and stability wise Civic is superior. At higher speeds Prius kind of gives a feeling that its gotten slippery through the air probably because of a super slippery aerodynamic body focussed towards economy. Acceleration wise Prius is slightly better till first 100.
Overall Prius feels very boring to drive as compared to Civic. Civic makes you feel younger while you drive it.