W.Salam
first thing you cannot reach Islamabad in single go, so much better break your journey into 2.
agar sirf app driver hain to yeh bht thaka dainy wala kaam hai.
i have done this trip multiple of time if you are travelling first time then keep below documents
Original NIC
Original License Valid
Original Book (if not registered on your name then authority letter also required)
Pay token tax and Put sticker on Screen and also keep tax slip.
get some 250-500 Rs highway insurance (sindh police will ask if they stop you)
ACLC NOC (useless in punjab, sindh police will ask if they stopped you)
Highway Code book
Tools
Basic tools
Flash Light
Jump Cables
Jack, Pana, Rod
Mix Fuse
extra relays
tow cable
check tyres, radiator, also check oil condition.
i Left 3.30am from karachi and reached BWP 7pm and night stay at BWP
Last time traveled on auto civic 2005 model, only stopped for break fast, lunch and call of nature and one stop for refuel after sukkur.
Karachi to Hyderabad via Motorway
Hyderabad to BWP n5 road condition is good,
i went to Lahore so i take m4 from multan. 50km Track from BWP to multan is not in good condition and under construction.
for further details you can call me on my number +92 331 525 3532