i have used both in the same car under same circumstances.
i find single channel radiator better.
In winters it takes lot of time to attain optimal temperature ( the t Stat valave present and working ) as there is increased amount of coolant needed to be warmed up and more area in contact with environment as compared to single channel.
in summer, its same, takes longer to attain optimal temperture and once the optimal temp is attained and rad fan is activated, it takes longer to reduce the temp upto acceptable level as there is more amount of coolant to be cooled down so rad fan has to work overtime.
plus the heat mass in conserable increased in the engine room, and it seems that it affects the AC performance as well.
single channel feel so effecient and works fast in my opinion.
just my two cents