A turbo cannot be reliable to a wide band of fuel quality because again, high compression is high compression, and bad-fuel-air mixture is going to pre-ignite and knock. And designing the turbo engine for that with low quality fuel will either make a heavier block or a costly block (expensive alloys), or less HP (which defeats the purpose manufacturers are trying to solve).
But turbos have come a long way recently, but will take probably a leap in metallurgy and manufacturing techniques to make econobox turbos as reliable and long lasting as NAs.
The new LC-300 has a turbo and I have same concerns with it.
Doesn't have to be an engine failure to make your life hard. If, like here in PK, Turbo require frequent spark plug and cat converter replacement, thats unreliable enough for me because its maintenance intensive, and it's costly.